Biography
Ascher is a graduate of the University of Michigan, Ann Arbor, where she earned her medical degree. She completed a general surgery residency and clinical transplant fellowship at the University of Minnesota, where she later joined the faculty and became clinical director of the liver transplant program.
Ascher is a fellow of the American College of Surgeons. She is a member of numerous other medical societies, including the American Society of Transplant Surgeons, in which she has served as president.
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Education
Institution | Degree | Dept or School | End Date |
---|---|---|---|
University of Minnesota | Fellowship | Transplant Surgery | 1982 |
University of Minnesota | Residency | General Surgery | 1981 |
University of Michigan | 1974 |
Board Certifications
- American Board of Surgery, 1982, renewed 2012
Clinical Expertise
End-Stage Kidney Disease
Fulminant Hepatic Failure
Hepatitis B
Hepatitis C
Hepatocellular Carcinoma (Liver Cancer)
Kidney Transplantation
Liver Cysts
Living Donor Kidney Transplantation
Living Donor Liver Transplantation
Liver Transplantation
Non-alcoholic Fatty Liver Disease
Pediatric Liver Transplantation
Pediatric Kidney Transplantation
Portal Hypertension
In the News
Grants and Funding
- ALLOGRAFT RESPONSE TO LIVER TISSUE | NIH | 1988-09-30 - 1995-09-29 | Role: Principal Investigator
- LIVER TRANSPLANTATION CENTERS | NIH/NIDDK | 1990-01-01 - 1995-03-31 | Role: Principal Investigator
- ORGAN TRANSPLANTS: ANALYSIS OF MIGRATING LYMPHOCYTES | NIH | 1984-07-01 - 1987-06-30 | Role: Principal Investigator
Research Narrative
I. RECURRENT DISEASE AFTER LIVER TRANSPLANT
The NIH Liver Transplant Data Base has been extended to address the important issue of disease recurrence after liver transplantation. Although short term liver transplant results have improved markedly over the past ten years, it is apparent that disease recurrence is an important source of patient morbidity and graft loss. Long term following of greater than 1000 patients in the Liver Transplant Data Base will facilitate our understanding of the factors associated with graft recurrence.
II. EXPANDED CRITERIA FOR LIVER TRANSPLANT FOR HEPATOCELLULAR CARCINOMA
We have redefined the criteria for liver transplantation beyond the Milan criteria. The UCSF criteria enables additional patients to benefit from liver transplants without compromising outcome.
Research Interests
- Clinical Transplantation
- Recurrence After Liver Transplantation
- Transplant Policy
- Transplant Ethics
Publications
- Proposed US Legislation to Pay Kidney Donors: Counter-productive and Against Global Ethical Standards.| | PubMed
- Promoting Equitable and Affordable Patient Access to Safe and Effective Innovations in Donation and Transplantation of Substances of Human Origin and Derived Therapies.| | PubMed
- A Last Hurrah: Reply to Sharif et al Regarding China.| | PubMed
- Anesthesia and Critical Care for the Prediction and Prevention for Small-for-size Syndrome: Guidelines from the ILTS-iLDLT-LTSI Consensus Conference.| | PubMed
- Management of Established Small-for-size Syndrome in Post Living Donor Liver Transplantation: Medical, Radiological, and Surgical Interventions: Guidelines From the ILTS-iLDLT-LTSI Consensus Conference.| | PubMed
- Post Living Donor Liver Transplantation Small-for-size Syndrome: Definitions, Timelines, Biochemical, and Clinical Factors for Diagnosis: Guidelines From the ILTS-iLDLT-LTSI Consensus Conference.| | PubMed
- DCD liver transplant in patients with a MELD over 35.| | PubMed
- Preventing Small-for-size Syndrome in Living Donor Liver Transplantation: Guidelines From the ILTS-iLDLT-LTSI Consensus Conference.| | PubMed
- Organ Donation and Transplantation in China.| | PubMed
- Sex-based Disparities in Access to Liver Transplantation for Waitlisted Patients With Model for End-stage Liver Disease Score of 40.| | PubMed
- Comments on Experience With Establishing a Robotic Donor Hepatectomy Program for Pediatric Liver Transplantation.| | PubMed
- The John S. Najarian symposium: The past, present, and future of surgery and transplantation, May 20, 2022, Minneapolis, MN.| | PubMed
- Addressing sex-based disparities in solid organ transplantation in the United States - a conference report.| | PubMed
- Comparison of Biliary Complications Rates After Brain Death, Donation After Circulatory Death, and Living-Donor Liver Transplantation: A Single-Center Cohort Study.| | PubMed
- The Reality of Inadequate Patient Care and the Need for a Global Action Framework in Organ Donation and Transplantation.| | PubMed
- Optimizing pre-donation physiologic evaluation for enhanced recovery after living liver donation - Systematic review and multidisciplinary expert panel recommendations.| | PubMed
- Novel Benchmark Values for Redo Liver Transplantation: Does the Outcome Justify the Effort?| | PubMed
- A novel microsurgical reconstruction technique in a living-related liver donor hepatic artery dissection using the native hepatic artery.| | PubMed
- Long-term Outcomes Following Kidney and Liver Transplant in Recipients With HIV.| | PubMed
- International Travel for Liver Transplantation: A Comprehensive Assessment of the Impact on the United States Transplant System.| | PubMed
- Advantages and Limitations of Clinical Scores for Donation After Circulatory Death Liver Transplantation.| | PubMed
- Expedited evaluation for liver transplantation: A critical look at processes and outcomes.| | PubMed
- Travel for Transplantation: A Review of Domestic and International Travel for Liver Transplantation in the United States.| | PubMed
- Surgical Trainee Well-Being: A Synergy of Individual and System-Level Interventions.| | PubMed
- Correction to: Expanding controlled donation after the circulatory determination of death: statement from an international collaborative.| | PubMed
- Meeting Report: First State of the Art Meeting on Gender Disparity in Kidney Transplantation in the Asia-Pacific.| | PubMed
- "The use of bilateral continuous erector spinae plane blocks for postoperative analgesia after right-sided living donor hepatectomy: A feasibility study".| | PubMed
- Retransplantation After Living Donor Liver Transplantation: Data from the Adult to Adult Living Donor Liver Transplantation Study.| | PubMed
- Obesity is a risk factor for progression to kidney transplant waitlisting after liver transplantation.| | PubMed
- The Importance of Bringing Transplantation Tolerance to the Clinic.| | PubMed
- Standardizing Discharge Opioid Prescriptions in Kidney Transplant Patients Decreases Opioid Usage.| | PubMed
- Live Donor Liver Transplantation in the United States: Impact of Share 35 on Live Donor Utilization.| | PubMed
- Enhanced Stress Resilience Training in Surgeons: Iterative Adaptation and Biopsychosocial Effects in 2 Small Randomized Trials.| | PubMed
- Expanding controlled donation after the circulatory determination of death: statement from an international collaborative.| | PubMed
- A world-wide survey on kidney transplantation practices in breast cancer survivors: The need for new management guidelines.| | PubMed
- Exploration of Individual and System-Level Well-being Initiatives at an Academic Surgical Residency Program: A Mixed-Methods Study.| | PubMed
- Opioid Use and Liver Transplantation.| | PubMed
- Setting rules for the sandbox: A response to "Successfully sharing the sandbox: A perspective on combined DCD liver and heart donor procurement".| | PubMed
- Expanding living donor liver transplantation: Report of first US living donor liver transplant chain.| | PubMed
- Opioid use prior to liver transplant is associated with increased risk of death after transplant.| | PubMed
- COVID-19 and Abdominal Transplant: A Stepwise Approach to Practice During Pandemic Conditions.| | PubMed
- In Memoriam: Dr. John Najarian, 1927-2020.| | PubMed
- Global Transplantation COVID Report March 2020.| | PubMed
- Training of Male and Female Surgical Residents.| | PubMed
- Author's Response.| | PubMed
- Implementing an opioid reduction protocol in renal transplant recipients.| | PubMed
- Quantifying Sex-Based Disparities in Liver Allocation.| | PubMed
- A Virtual Crossmatch-based Strategy Facilitates Sharing of Deceased Donor Kidneys for Highly Sensitized Recipients.| | PubMed
- Living Donor Liver Transplant for Alcoholic Liver Disease: Data from the Adult-to-adult Living Donor Liver Transplantation Study.| | PubMed
- Key factors for implementing mindfulness-based burnout interventions in surgery.| | PubMed
- The Utility of ECMO After Liver Transplantation: Experience at a High-volume Transplant Center and Review of the Literature.| | PubMed
- Glass Slippers and Glass Cliffs: Fitting In and Falling Off.| | PubMed
- Societal and Professional Obligation in the Care of the Living Organ Donor.| | PubMed
- Bi-organ paired exchange-Sentinel case of a liver-kidney swap.| | PubMed
- Efficacy of Mindfulness-Based Cognitive Training in Surgery: Additional Analysis of the Mindful Surgeon Pilot Randomized Clinical Trial.| | PubMed
- Call for an End to Unethical Transplant Practices: A Concerted Effort by the Transplant Community.| | PubMed
- Feasibility of Formal Mindfulness-Based Stress-Resilience Training Among Surgery Interns: A Randomized Clinical Trial.| | PubMed
- Deceased Donor Organ Transplantation Performed in the United States for Noncitizens and Nonresidents.| | PubMed
- The Impact of Renal Insufficiency After Liver Transplantation.| | PubMed
- Living Donor Liver Transplantation for Alcoholic Liver Disease.| | PubMed
- A Formula to Calculate Standard Liver Volume Using Thoracoabdominal Circumference.| | PubMed
- Burnout and Stress Among US Surgery Residents: Psychological Distress and Resilience.| | PubMed
- Opposition to irresponsible global kidney exchange.| | PubMed
- Clinical Trials for Immunosuppression in Transplantation: The Case for Reform and Change in Direction.| | PubMed
- Criminal Organ Retrieval: Unconscionable.| | PubMed
- The Transplantation Society Believes a Policy of Engagement Will Facilitate Organ Donation Reform in China.| | PubMed
- Biliary complications following living donor hepatectomy.| | PubMed
- Impact of Graft Selection on Donor and Recipient Outcomes After Living Donor Liver Transplantation.| | PubMed
- Medical Students' Perceptions of Surgeons: Implications for Teaching and Recruitment.| | PubMed
- Nancy L. Ascher, MD, PhD: Professor and Chair, Department of Surgery, UCSF; Past-President, ASTS; President-elect, The Transplantation Society.| | PubMed
- Improving interprofessional collaboration: evaluation of implicit attitudes in the surgeon-nurse relationship.| | PubMed
- Perceptions of surgeons: what characteristics do women surgeons prefer in a colleague?| | PubMed
- Patient perceptions of female surgeons: how surgeon demeanor and type of surgery affect patient preference.| | PubMed
- Ex vivo split-liver transplantation: the true right/left split.| | PubMed
- Left hepatectomy versus right hepatectomy for living donor liver transplantation: shifting the risk from the donor to the recipient.| | PubMed
- Asian American adolescents' willingness to donate organs and engage in family discussion about organ donation and transplantation.| | PubMed
- Use of living donor liver transplantation varies with the availability of deceased donor liver transplantation.| | PubMed
- Outcomes with split liver transplantation in 106 recipients: the University of California, San Francisco, experience from 1993 to 2010.| | PubMed
- Outcomes of surgical repair of bile leaks and strictures after adult-to-adult living donor liver transplant.| | PubMed
- Comparison of biliary complications in adult living-donor liver transplants performed at two busy transplant centers.| | PubMed
- Emergent orthotopic liver transplantation for hemorrhage from a giant cavernous hepatic hemangioma: case report and review.| | PubMed
- Development of the Organ Donation and Transplantation Knowledge Survey for use in Asian American adolescents.| | PubMed
- Left lobe adult-to-adult living donor liver transplantation: small grafts and hemiportocaval shunts in the prevention of small-for-size syndrome.| | PubMed
- Excellent outcome following down-staging of hepatocellular carcinoma prior to liver transplantation: an intention-to-treat analysis.| | PubMed
- Operating room assist: surgical mentorship and operating room experience for preclerkship medical students.| | PubMed
- Laparoscopic bariatric surgery improves candidacy in morbidly obese patients awaiting transplantation.| | PubMed
- Liver transplantation at UCSF--a 20-year experience.| | PubMed
- HIV-infected liver and kidney transplant recipients: 1- and 3-year outcomes.| | PubMed
- Liver transplantation for hepatocellular carcinoma: validation of the UCSF-expanded criteria based on preoperative imaging.| | PubMed
- A surgical skills elective to expose preclinical medical students to surgery.| | PubMed
- Tribute: Dr. Olga Jonasson. Born in Peoria, Illinois, August 12, 1934. Died in Chicago, Illinois, August 30, 2006.| | PubMed
- Enhancing the mission of academic surgery by promoting scientific writing skills.| | PubMed
- Central venous pressure monitoring during living right donor hepatectomy.| | PubMed
- A randomized trial of exercise and dietary counseling after liver transplantation.| | PubMed
- Report of a National Conference on Donation after cardiac death.| | PubMed
- A prospective study on downstaging of hepatocellular carcinoma prior to liver transplantation.| | PubMed
- The Department of Surgery, University of California, San Francisco.| | PubMed
- High incidence of recurrence and hematologic events following liver transplantation for Budd-Chiari syndrome.| | PubMed
- The use of stents for duct-to-duct anastomoses of biliary reconstruction in orthotopic liver transplantation.| | PubMed
- The impact of pre-operative loco-regional therapy on outcome after liver transplantation for hepatocellular carcinoma.| | PubMed
- Objective measures of health-related quality of life over 24 months post-liver transplantation.| | PubMed
- Liver transplantation for hepatocellular carcinoma: lessons from the first year under the Model of End-Stage Liver Disease (MELD) organ allocation policy.| | PubMed
- New onset diabetes mellitus after liver transplantation: the critical role of hepatitis C infection.| | PubMed
- Split-liver transplantation in the United States: outcomes of a national survey.| | PubMed
- Prediction of survival after liver retransplantation for late graft failure based on preoperative prognostic scores.| | PubMed
- Death from donor-transmitted malignancy despite emergency liver retransplantation.| | PubMed
- Expanding the donor pool: can the Spanish model work in the United States?| | PubMed
- Effects of exercise training on coronary heart disease risk factors in renal transplant recipients.| | PubMed
- Kidney and liver transplantation in human immunodeficiency virus-infected patients: a pilot safety and efficacy study.| | PubMed
- A follow-up analysis of the pattern and predictors of dropout from the waiting list for liver transplantation in patients with hepatocellular carcinoma: implications for the current organ allocation policy.| | PubMed
- Analysis of research projects in living donor organ transplantation.| | PubMed
- What's new in general surgery: transplantation.| | PubMed
- Intraoperative hemodynamics and liver function in adult-to-adult living liver donors.| | PubMed
- Liver transplantation for hepatocellular carcinoma: analysis of survival according to the intention-to-treat principle and dropout from the waiting list.| | PubMed
- Liver transplantation for hepatocellular carcinoma: comparison of the proposed UCSF criteria with the Milan criteria and the Pittsburgh modified TNM criteria.| | PubMed
- Allograft rejection in pediatric liver transplantation: Comparison between cadaveric and living related donors.| | PubMed
- A randomized trial of exercise training after renal transplantation.| | PubMed
- Donor health assessment after living-donor liver transplantation.| | PubMed
- Liver transplantation for nonviral, nonmalignant diseases:problem of recurrence.| | PubMed
- Posttransplantation growth in pediatric liver recipients.| | PubMed
- Solid organ transplantation in HIV-positive patients.| | PubMed
- Mixed allogeneic chimerism as a reliable model for composite tissue allograft tolerance induction across major and minor histocompatibility barriers.| | PubMed
- Liver transplantation for hepatocellular carcinoma: expansion of the tumor size limits does not adversely impact survival.| | PubMed
- Physical activity and health-related quality of life in liver transplant recipients.| | PubMed
- Posttransplantation lymphoproliferative disorders in pediatric patients undergoing liver transplantation.| | PubMed
- Immunosuppressant substitutes in liver transplantation.| | PubMed
- A calcineurin inhibitor-sparing regimen with sirolimus, mycophenolate mofetil, and anti-CD25 mAb provides effective immunosuppression in kidney transplant recipients with delayed or impaired graft function.| | PubMed
- Experience with the use of sirolimus in liver transplantation--use in patients for whom calcineurin inhibitors are contraindicated.| | PubMed
- Surgical anatomy of the left lateral segment as applied to living-donor and split-liver transplantation: a clinicopathologic study.| | PubMed
- Prolonged cold ischemia time obviates the benefits of 0 HLA mismatches in renal transplantation.| | PubMed
- A non-cleavable mutant of Fas ligand does not prevent neutrophilic destruction of islet transplants.| | PubMed
- A dendritic cell line genetically modified to express CTLA4-IG as a means to prolong islet allograft survival.| | PubMed
- Flow cytometry crossmatching as a predictor of acute rejection in sensitized recipients of cadaveric renal transplants.| | PubMed
- HCV-related fibrosis progression following liver transplantation: increase in recent years.| | PubMed
- Experience with daclizumab in liver transplantation: renal transplant dosing without calcineurin inhibitors is insufficient to prevent acute rejection in liver transplantation.| | PubMed
- Liver transplantation for autoimmune hepatitis: rejection and recurrence.| | PubMed
- Four-year follow-up of mycophenolate mofetil for graft rescue in liver allograft recipients.| | PubMed
- Mycophenolate mofetil, microemulsion cyclosporine, and prednisone as primary immunosuppression for pediatric liver transplant recipients.| | PubMed
- Effect of systemic cyclosporine on tumor recurrence after liver transplantation in a model of hepatocellular carcinoma.| | PubMed
- Hepatic artery pseudoaneurysm with hemobilia following angioplasty after liver transplantation.| | PubMed
- Donor-specific tolerance induction in composite tissue allografts.| | PubMed
- Hepatitis after liver transplantation: the role of the known and unknown viruses.| | PubMed
- Possible recurrence of primary sclerosing cholangitis following living-related liver transplantation: report of a case.| | PubMed
- Biliary complications of reduced-organ liver transplantation.| | PubMed
- Incidence and clinical consequences of surface and polymerase gene mutations in liver transplant recipients on hepatitis B immunoglobulin.| | PubMed
- The role of pediatricians in the care of children with liver transplants.| | PubMed
- Tolerance induction using bone marrow transplantation.| | PubMed
- Single-center long-term results of renal transplantation for IgA nephropathy.| | PubMed
- Risks associated with conversion of stable patients after liver transplantation to the microemulsion formulation of cyclosporine.| | PubMed
- Fas ligand expression on islets as well as multiple cell lines results in accelerated neutrophilic rejection.| | PubMed
- Predictors of the cost of liver transplantation.| | PubMed
- Progress in transgenic pigs for xenotransplantation.| | PubMed
- Quo vadis, my transplant fellow: a discussion of transplant surgery fellowship training activity in the United States and Canada: 1991-1997. Education Committee of the American Society of Transplant Surgeons.| | PubMed
- Interleukin-2 receptor antibody therapy.| | PubMed
- Pathological changes in yearly protocol liver biopsy specimens from healthy pediatric liver recipients.| | PubMed
- The impact of surgical complications after liver transplantation on resource utilization.| | PubMed
- Planned exploration of pediatric liver transplant recipients reduces posttransplant morbidity and lowers length of hospitalization.| | PubMed
- Retransplantation of patients with severe posttransplant hepatitis B in the first allograft.| | PubMed
- Auxiliary liver transplant in fulminant failure.| | PubMed
- Increased immune responses to regenerating partial liver grafts in the rat.| | PubMed
- Hepatitis G virus in patients with cryptogenic liver disease undergoing liver transplantation.| | PubMed
- A controlled analysis of the transjugular intrahepatic portosystemic shunt in liver transplant recipients. The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Liver Transplantation Database.| | PubMed
- The role of the host immune state in recurrent hepatitis C.| | PubMed
- Antibody to the host cellular gene-derived epitope GOR-1 in liver transplant recipients with hepatitis C virus infection.| | PubMed
- Clonal deletion is one mechanism responsible for tolerance in mixed hematopoietic chimeras.| | PubMed
- Hepatitis G virus infection in patients with hepatitis C virus infection undergoing liver transplantation.| | PubMed
- Prophylaxis in liver transplant recipients using a fixed dosing schedule of hepatitis B immunoglobulin.| | PubMed
- Severity of liver disease in liver transplantation recipients with hepatitis C virus infection: relationship to genotype and level of viremia.| | PubMed
- Functional analysis of grafts from living donors. Implications for the treatment of older recipients.| | PubMed
- Failure patterns of cryopreserved vein grafts in liver transplantation.| | PubMed
- Liver transplantation improves survival of rats bearing hepatoma-3924A.| | PubMed
- SCID mouse as a model for transplantation studies.| | PubMed
- Decreased mortality from technical failure improves results in pediatric liver transplantation.| | PubMed
- Hepatotoxins and liver transplantation decrease pulmonary metastases in rats with hepatoma.| | PubMed
- Living related donor liver transplantation: the UCSF experience.| | PubMed
- Strategies for tolerance induction: potential applications in living donor liver transplantation.| | PubMed
- Fifty-percent partial liver transplantation in the rat.| | PubMed
- Expanding the immunosuppressive repertoire.| | PubMed
- Advances in biliary reconstruction after liver transplantation.| | PubMed
- Interferon alfa for recurrent hepatitis B infection after liver transplantation.| | PubMed
- Transmission of hepatitis B virus through allotransplantation.| | PubMed
- United Network for Organ Sharing center-specific data: our report card.| | PubMed
- Incidence and significance of Aspergillus cultures following liver and kidney transplantation.| | PubMed
- The use of the T tube after orthotopic liver transplantation.| | PubMed
- Cryoglobulinemia presenting after liver transplantation.| | PubMed
- Hepatitis C dilemma?| | PubMed
- Detection of hepatitis C after liver transplantation. Four serologic tests compared.| | PubMed
- Hepatic granulomas following liver transplantation. Clinicopathologic features in 42 patients.| | PubMed
- Increased efficacy of CSA following rearterialization in the rat OLTX model.| | PubMed
- Influence of donor age on graft survival after liver transplantation--United Network for Organ Sharing Registry.| | PubMed
- Issues in xenotransplantation.| | PubMed
- Posttransplantation lymphoproliferative disorder in patients under primary tacrolimus (FK 506) immunosuppression.| | PubMed
- Liver transplantation for sclerosing cholangitis.| | PubMed
- Total vascular exclusion for major hepatectomy in patients with abnormal liver parenchyma.| | PubMed
- Amelioration of acute GVHD disease and reestablishment of tolerance by short term treatment with anti TCR antibody.| | PubMed
- Liver transplantation for hepatocellular carcinoma: results with preoperative chemoembolization.| | PubMed
- Primary sclerosing cholangitis: liver transplantation or biliary surgery.| | PubMed
- Time course of cyclosporine and ist motabolites in blood, liver and spleen of naive Lewis rats: comparison with preliminary data obtained in transplanted animals.| | PubMed
- Two-year outcome following transjugular intrahepatic portosystemic shunt for variceal bleeding: results in 90 patients.| | PubMed
- Hepatocyte transplantation.| | PubMed
- FK506 (tacrolimus) compared with cyclosporine for primary immunosuppression after pediatric liver transplantation. Results from the U.S. Multicenter Trial.| | PubMed
- Impact of transjugular intrahepatic portosystemic shunts on liver transplantation: a controlled analysis. NIDDK Liver Transplantation Database.| | PubMed
- The risk of transmission of hepatitis B from HBsAg(-), HBcAb(+), HBIgM(-) organ donors.| | PubMed
- Fulminant hepatic failure: summary of a workshop.| | PubMed
- Immunosuppressive therapy in liver transplantation: principles and practice.| | PubMed
- Microchimerism in organ transplantation.| | PubMed
- Effect of cyclosporine dosing on creatinine levels in hepatic transplant recipients.| | PubMed
- Interferon-alpha therapy for hepatitis C virus infection after liver transplantation.| | PubMed
- Liver transplantation for hepatitis C virus-related cirrhosis.| | PubMed
- Predicting recidivism after orthotopic liver transplantation for alcoholic liver disease.| | PubMed
- Enhancement of islet allograft survival in mice treated with MHC class I specific F(ab')2 alloantibody.| | PubMed
- Quantitation of hepatitis C virus RNA in liver transplant recipients.| | PubMed
- beta-2 Microglobulin gene disruption prolongs murine islet allograft survival in NOD mice.| | PubMed
- Prolongation of in vivo mouse islet allograft survival by modulation of MHC class I antigen.| | PubMed
- The increased efficacy and decreased nephrotoxicity of a cyclosporine liposome.| | PubMed
- "Occult" hepatitis B virus as source of infection in liver transplant recipients.| | PubMed
- Liver transplantation and the Najarian footprint.| | PubMed
- Major histocompatibility complex class I deficiency prolongs islet allograft survival.| | PubMed
- Reversal of chronic rejection after treatment failure with FK506 and RS61443.| | PubMed
- Immunosuppressive therapy as a determinant of transplantation outcomes.| | PubMed
- Liver transplantation for fulminant hepatic failure.| | PubMed
- New immunologic insights into mechanisms of allograft rejection.| | PubMed
- Creation of transjugular intrahepatic portosystemic shunts with the wallstent endoprosthesis: results in 100 patients.| | PubMed
- IL-2 and IL-5 gene expression in response to alloantigen in liver allograft recipients and in vitro.| | PubMed
- Nonoperative management of biliary leaks after orthotopic liver transplantation.| | PubMed
- Cirrhosis of undefined pathogenesis: absence of evidence for unknown viruses or autoimmune processes.| | PubMed
- Evidence for a nonclassical pathway of graft rejection involving interleukin 5 and eosinophils.| | PubMed
- Hepatitis C and B in liver transplantation.| | PubMed
- Immunosuppression and rejection in liver transplantation.| | PubMed
- Maintenance immunosuppression with prednisone and RS-61443 alone following liver transplantation.| | PubMed
- Transjugular intrahepatic portacaval stent shunts in patients with renal insufficiency.| | PubMed
- Estimates of organ-specific donor availability for the United States.| | PubMed
- Intragraft eosinophilia and interleukin-5 mRNA accompany liver allograft rejection.| | PubMed
- Isolation of functional MHC class I-deficient islet cells.| | PubMed
- Orthotopic liver transplantation for end-stage alcoholic liver disease.| | PubMed
- Prognostic factors for successful conversion from cyclosporine to FK 506-based immunosuppressive therapy for refractory rejection after liver transplantation. US Multicenter FK 506 Liver Study Group.| | PubMed
- RS-61443 for treatment-resistant human liver rejection.| | PubMed
- Standard sequential immunosuppression with Minnesota antilymphoblast globulin and cyclosporine vs FK 506: a comparison of early nephrotoxicity.| | PubMed
- T-cell receptor-V alpha gene use in sequential liver allograft biopsies.| | PubMed
- Use of FK 506 for the prevention of recurrent allograft rejection after successful conversion from cyclosporine for refractory rejection. US Multicenter FK 506 Liver Study Group.| | PubMed
- Use of Prograf (FK 506) as rescue therapy for refractory rejection after liver transplantation. US Multicenter FK 506 Liver Study Group.| | PubMed
- Liver transplantation at the University of California, San Francisco.| | PubMed
- Incidence and diagnostic features of macroregenerative nodules vs. small hepatocellular carcinoma in cirrhotic livers.| | PubMed
- Lipopeliosis: fat induced sinusoidal dilatation in transplanted liver mimicking peliosis hepatis.| | PubMed
- Hepatitis C viral infection in liver transplant recipients.| | PubMed
- Pulmonary hypertension associated with liver disease is not reversible after liver transplantation.| | PubMed
- Transjugular intrahepatic portosystemic shunts: preliminary results in 25 patients.| | PubMed
- A modified vascular "sleeve" anastomosis for rearterialization in orthotopic liver transplantation in rats.| | PubMed
- Intracranial pressure monitoring and liver transplantation for fulminant hepatic failure.| | PubMed
- Recurrent and acquired hepatitis C viral infection in liver transplant recipients.| | PubMed
- Hepatitis B virus and apparent fulminant non-A, non-B hepatitis.| | PubMed
- Cell subsets responding to purified hepatocytes and evidence of indirect recognition of hepatocyte major histocompatibility complex class I antigen. I. The role of L3T4+ T cells in the development of allospecific cytotoxicity in hepatocyte-sponge matrix a| | PubMed
- Cell subsets responding to purified hepatocytes and evidence of indirect recognition of hepatocyte major histocompatibility complex class I antigen. II. In vitro-generated "memory" cells to class I+ class II- hepatocytes.| | PubMed
- Using transjugular intrahepatic portosystemic shunts to control variceal bleeding before liver transplantation.| | PubMed
- Intragraft cytokine profile during human liver allograft rejection.| | PubMed
- Maintenance immunosuppression after liver transplantation.| | PubMed
- The potential supply of organ donors. An assessment of the efficacy of organ procurement efforts in the United States.| | PubMed
- Anesthetic care of patients with Crigler-Najjar syndrome.| | PubMed
- Efficacy and toxicity of FK 506 for the treatment of resistant rejection in liver transplant patients.| | PubMed
- Similar clinical presentation of neurotoxicity following FK 506 and cyclosporine in a liver transplant recipient.| | PubMed
- Azathioprine hepatotoxicity after liver transplantation.| | PubMed
- Histopathologic study of transjugular intrahepatic portosystemic shunts.| | PubMed
- Evidence for direct and indirect pathways in the generation of the alloimmune response against pancreatic islets.| | PubMed
- Demonstration of local immunosuppression with methylprednisolone in the sponge matrix allograft model.| | PubMed
- Graft vs. host disease after liver transplantation in humans: a report of four cases.| | PubMed
- Hepatitis C virus not found in fulminant non-A, non-B hepatitis.| | PubMed
- Early liver transplantation is indicated for tyrosinemia type I.| | PubMed
- Intrahepatic portocaval shunt for variceal hemorrhage prior to liver transplantation.| | PubMed
- Cladosporium trichoides cerebral phaeohyphomycosis in a liver transplant recipient. Report of a case.| | PubMed
- Hepatitis C in patients undergoing liver transplantation.| | PubMed
- Allogeneic hepatocytes stimulate the production of immunoregulatory molecules in mixed lymphocyte hepatocyte cultures.| | PubMed
- An improved method for the detection of soluble interleukin 2 receptors in liver transplant recipients by flow cytometry.| | PubMed
- Characterization of a cyclosporine-containing liposome.| | PubMed
- Comparison of ELISA and a flow cytometric method in the daily monitoring of soluble interleukin 2 receptors in liver transplant recipients.| | PubMed
- Comparison of three regimens for cytomegalovirus prophylaxis in 147 liver transplant recipients.| | PubMed
- Hepatitis C in liver transplant recipients.| | PubMed
- Lack of class II antigen expression on hepatocytes profoundly affects CTL development in vitro and in vivo.| | PubMed
- MHC expression on human hepatocytes before and after isolation.| | PubMed
- The alloimmune response against pancreatic islets is generated by both direct and indirect pathways.| | PubMed
- Persistent hepatitis B virus following interferon alfa therapy and liver transplantation.| | PubMed
- Percutaneous transhepatic portal vein angioplasty and stent placement after liver transplantation: early experience.| | PubMed
- Examination of vascular anastomoses during liver transplantation by intraoperative Doppler duplex scanning.| | PubMed
- Role of macrophages in the immune response to hepatocytes.| | PubMed
- Liver transplantation for severe Amanita phalloides mushroom poisoning.| | PubMed
- The management of T tube leaks in orthotopic liver transplant recipients with endoscopically placed nasobiliary catheters.| | PubMed
- The alloimmune response to murine islets occurs via indirect antigen presentation to LYT2+ and L3T4+ lymphocytes.| | PubMed
- Comparison of in vivo and in vitro immune response to purified hepatocytes.| | PubMed
- Massive venous air embolism during orthotopic liver transplantation.| | PubMed
- Local prednisolone infusion of canine renal allografts.| | PubMed
- The pharmacokinetic advantage of local 6-mercaptopurine infusion in a canine renal transplant model.| | PubMed
- Transplant renal artery stenosis.| | PubMed
- Gastric bezoar after hepatic transplantation.| | PubMed
- Liver transplantation in a patient with protoporphyria.| | PubMed
- Hemodynamic changes on clamping and unclamping of major vessels during liver transplantation.| | PubMed
- Selection criteria for liver transplantation donors.| | PubMed
- Modulation of MHC class I antigen decreases pancreatic islet immunogenicity.| | PubMed
- Biliary complications after liver transplantation in children.| | PubMed
- Adult kidney retransplantation: evolution of treatment and results over 25 years at the University of Minnesota.| | PubMed
- Comparative in vitro immunogenicity of cultured murine islets and hepatocytes.| | PubMed
- Factors influencing early survival after liver transplantation.| | PubMed
- Frequency of precursor cytotoxic T lymphocytes correlates with outcome following heart-lung and pancreatic islet transplantation.| | PubMed
- Hereditary tyrosinemia type I (chronic form): pathologic findings in the liver.| | PubMed
- In vitro immunosuppressive effects of murine hepatocyte cytosol.| | PubMed
- L3T4+,LyT2- and LyT2+,L3T4- T cells participate in the generation of allospecific cytotoxicity in response to MHC class I+ hepatocytes.| | PubMed
- Long-term outcome of renal transplantation in patients with systemic lupus erythematosus.| | PubMed
- Pediatric liver transplantation across ABO blood group barriers.| | PubMed
- Rapid infusion technique as a safe alternative to veno-venous bypass in orthotopic liver transplant (TX).| | PubMed
- Afferent and efferent pathways in T cell responses to MHC class I+, II-hepatocytes.| | PubMed
- Effect of immunodepletion of MHC class II-positive cells from pancreatic islets on generation of cytotoxic T-lymphocytes in mixed islet-lymphocyte coculture.| | PubMed
- Generation of allospecific cytolytic T-lymphocytes stimulated by pure pancreatic beta-cells in absence of Ia+ dendritic cells.| | PubMed
- Liver transplantation today.| | PubMed
- Pharmacokinetics of 6-thiouric acid and 6-mercaptopurine in renal allograft recipients after oral administration of azathioprine.| | PubMed
- Responder T-cell subsets and antigenic stimulus in mixed lymphocyte-hepatocyte culture.| | PubMed
- An implantable pump for intrarenal infusion of immunosuppressants in a canine autotransplant model.| | PubMed
- Infection and rejection of primary hepatic transplant in 93 consecutive patients treated with triple immunosuppressive therapy.| | PubMed
- Orthotopic liver transplantation: nonoperative management of early, acute portal vein thrombosis.| | PubMed
- Single-center 1-15-year results of renal transplantation in patients with systemic lupus erythematosus.| | PubMed
- [Comparison of the results of liver transplantation in children and adults].| | PubMed
- Couette membrane filtration with constant shear stress.| | PubMed
- In vitro generated allospecific cytolytic T lymphocytes injure pancreatic islets.| | PubMed
- A single-center experience of renal transplantation in thirteen Jehovah's Witnesses.| | PubMed
- Adjunctive azathioprine and antilymphocyte serum immunosuppression with cyclosporine.| | PubMed
- Effects of HLA matching in cadaver renal transplants.| | PubMed
- Erythrocytosis and thromboembolic complications after renal transplantation: results from a randomized trial of cyclosporine versus azathioprine-antilymphocyte globulin.| | PubMed
- Imaging of vascular complications after hepatic transplantation.| | PubMed
- Biliary complications after liver transplantation in patients with preexisting sclerosing cholangitis.| | PubMed
- Pancreatic islets generate allospecific cytolytic T lymphocytes in a mixed lymphocyte-islet culture.| | PubMed
- Imaging of renal transplants.| | PubMed
- Lymphocyte traffic and distribution after sponge matrix allograft using limiting dilution analysis.| | PubMed
- The contribution of natural killer cells to the allograft response.| | PubMed
- Characterization of natural killer activity in sponge matrix allografts.| | PubMed
- A randomized trial comparing cyclosporine with antilymphoblast-globulin-azathioprine for renal allograft recipients. Results at 2 1/2-6 years.| | PubMed
- Failure of freshly inplanted alloantigen in vivo to attract circulating allosensitized lymphocytes.| | PubMed
- ABO-compatible mismatching decreases 5-year actuarial graft survival after renal transplantation.| | PubMed
- Thromboembolic complications in renal allograft recipients. A report from the prospective randomized study of cyclosporine versus azathioprine-antilymphocyte globulin.| | PubMed
- Mixed islet-lymphocyte culture as a model for pancreatic islet immunogenicity and cell-mediated immune injury.| | PubMed
- Suppression of macrophage-mediated lymphocyte recruitment by local but not systemic steroids.| | PubMed
- The impact of cyclosporine and combination immunosuppression on the incidence of posttransplant diabetes in renal allograft recipients.| | PubMed
- Abdominal sonography after hepatic transplantation: results in 36 patients.| | PubMed
- Hepatic regenerating nodules in hereditary tyrosinemia.| | PubMed
- Major histocompatibility complex class I antigens on hepatocytes in human liver grafts.| | PubMed
- Pediatric liver transplantation using combination immunosuppressive therapy.| | PubMed
- Reperfusion coagulopathy during human liver transplantation.| | PubMed
- Liver allograft transplantation: postoperative CT findings.| | PubMed
- Hepatitis-associated aplastic anemia after liver transplantation.| | PubMed
- Kidney transplantation in diabetic patients.| | PubMed
- Contribution of extrahepatic tissues to biochemical abnormalities in hereditary tyrosinemia type I: study of three patients after liver transplantation.| | PubMed
- Ultrasound and computed tomographic evaluation in hepatic transplantation.| | PubMed
- An analysis of histological prognostic features of liver allograft rejection based on 270 serial biopsies.| | PubMed
- Can renal transplantation be done safely without prior dialysis therapy?| | PubMed
- Class I major histocompatibility complex antigens are induced on hepatocytes in rejecting human liver grafts.| | PubMed
- Cloned T cells do not require host H-2 restrictions to elicit delayed-type hypersensitivity.| | PubMed
- Compartmentalization and lymphocyte traffic after allograft challenge.| | PubMed
- Cox regression analysis of outcome risk factors in 519 renal allograft recipients.| | PubMed
- Designation of liver transplant centers in the United States.| | PubMed
- Detrimental effect of ABO mismatching in renal transplantation.| | PubMed
- Effector mechanisms in allograft rejection.| | PubMed
- First kidney transplants in children 5 years of age or younger.| | PubMed
- Frequency of diabetes-related complications in renal allograft recipients prospectively randomized to cyclosporine or azathioprine.| | PubMed
- HLA-DR tissue typing may be ignored for first but not subsequent cadaver renal transplants.| | PubMed
- In vivo macrophage-directed lymphocyte traffic requires macrophage activation.| | PubMed
- Plasma amino acid clearance predicts hepatic recovery after normothermic anoxia and cold preservation.| | PubMed
- Prognostic perioperative factors predicting the outcome of liver transplantation.| | PubMed
- Purified hepatocytes can stimulate allospecific cytolytic T lymphocytes in a mixed lymphocyte-hepatocyte culture.| | PubMed
- Renal allograft survival in patients with positive donor-specific B lymphocyte crossmatches.| | PubMed
- The role of natural killer cells in the allograft response.| | PubMed
- Thromboembolic complications after renal transplantation: results from the randomized trial of cyclosporine v azathioprine-antilymphocyte globulin.| | PubMed
- Use of triple therapy and percutaneous needle biopsy to minimize graft failure following liver transplantation.| | PubMed
- Increased expression of class I major histocompatibility complex antigens on hepatocytes in rejecting human liver allografts.| | PubMed
- Liver allograft rejection. An analysis of the use of biopsy in determining outcome of rejection.| | PubMed
- Renal transplantation done safely without prior chronic dialysis therapy.| | PubMed
- MR evaluation of the portal vein in pediatric liver transplant candidates.| | PubMed
- The outcome of 304 primary renal transplants in children (1968-1985).| | PubMed
- Lymphocytes capable of mediating delayed-type hypersensitivity reactions accumulate within sponge matrix allografts.| | PubMed
- Current results in pediatric renal transplantation at the University of Minnesota.| | PubMed
- Fulminant Wilson's disease treated with postdilution hemofiltration and orthotopic liver transplantation.| | PubMed
- Early and late effects of two immunosuppressive drug protocols on recipients of renal allografts: results of the Minnesota randomized trial comparing cyclosporine versus antilymphocyte globulin-azathioprine.| | PubMed
- New immunosuppressive drug combinations for mismatched related and cadaveric renal transplantation.| | PubMed
- Renal transplant immunity and immunosuppression.| | PubMed
- Scintigraphic evaluation of liver transplant function.| | PubMed
- The effects of delayed function on recipients of cadaver renal allografts. A study of 158 patients randomized to cyclosporine or ALG-azathioprine.| | PubMed
- The migration of activated T lymphocytes in vitro. III. Paralysis and recovery of locomotor function during mitosis.| | PubMed
- Alterations in amino acid clearance during ischemia predict hepatocellular ATP changes.| | PubMed
- Management and prevention of cyclosporine nephrotoxicity after renal transplantation: use of low doses of cyclosporine, azathioprine, and prednisone.| | PubMed
- Results of the Minnesota randomized prospective trial of cyclosporine versus azathioprine-antilymphocyte globulin for immunosuppression in renal allograft recipients.| | PubMed
- A single institution, randomized, prospective trial of cyclosporin versus azathioprine-antilymphocyte globulin for immunosuppression in renal allograft recipients.| | PubMed
- Information and long-term follow-up of a large number of related kidney donors at a single institution.| | PubMed
- Persistent succinylacetone excretion after liver transplantation in a patient with hereditary tyrosinaemia type I.| | PubMed
- Studies on living related kidney donors at a single institution.| | PubMed
- A functional assay for cyclosporine in patient serum.| | PubMed
- Comparison of modes of action of different immunosuppressive agents.| | PubMed
- Long-term effect of splenectomy versus no splenectomy in renal transplant patients. Reanalysis of a randomized prospective study.| | PubMed
- Similar renal allograft functional survival rates for kidneys from sibling donors matched for zero-versus-one haplotype with the recipient.| | PubMed
- Liver transplantation.| | PubMed
- Orthotopic liver transplantation: a pathological study of 63 serial liver biopsies from 17 patients with special reference to the diagnostic features and natural history of rejection.| | PubMed
- Survival rates of 2,728 patients with end-stage renal disease.| | PubMed
- Metabolism during hepatic transplantation: indicators of allograft function.| | PubMed
- Results of renal transplantation in diabetics at the University of Minnesota since 1979, including a comparison of outcome in diabetic and nondiabetic recipients randomized to cyclosporine versus azathioprine for immunosuppression.| | PubMed
- Comparison of azathioprine-antilymphocyte globulin versus cyclosporine in renal transplantation.| | PubMed
- Hepatic transplantation and biliary atresia: early experience in eight patients.| | PubMed
- Cellular basis of allograft rejection.| | PubMed
- Cyclosporine immunosuppression.| | PubMed
- Maturation of cytotoxic T cells within sponge matrix allografts.| | PubMed
- The community physician and liver transplantation.| | PubMed
- The migration of activated murine T lymphocytes in vitro. II. Evidence for differential locomotion of T cell subsets.| | PubMed
- Cellular events within the rejecting allograft.| | PubMed
- Maturation of cytotoxic effector cells at the site of allograft rejection.| | PubMed
- Migration of mouse lymphocytes in vitro. I. Normal lymph node lymphocytes.| | PubMed
- Migratory behavior of lymphocytes during allograft rejection.| | PubMed
- Evidence for local helper and suppressor function at the site of allograft rejection.| | PubMed
- Radiolabeled autologous leukocyte scanning in abscess detection.| | PubMed
- Specific and nonspecific infiltration of sponge matrix allografts by specifically sensitized cytotoxic lymphocytes.| | PubMed
- Effects of HLA-A and B matching on success of cadaver grafts at a single center.| | PubMed
- Epstein-Barr virus antibody responses and clinical illness in renal transplant recipients.| | PubMed
- Indium 111 autologous tagged leukocytes in the diagnosis of intraperitoneal sepsis.| | PubMed
- Partial characterization of cytotoxic cells infiltrating sponge matrix allografts.| | PubMed
- Causes and management of rejection.| | PubMed
- Relative absence of helper cells in rejecting allografts.| | PubMed
- 100 HLA-identical sibling transplants. Prognostic factors other than histocompatibility.| | PubMed
- 100 second renal allografts from a single transplantation institution.| | PubMed
- Graft rejection in donor-recipient pairs with differing of H-2 loci.| | PubMed
- Local graft irradiation: effect on cytotoxic cell infiltration.| | PubMed
- Jaundice after renal allotransplantation.| | PubMed
- Tuberculous joint disease in transplant patients.| | PubMed
- Listeria infection in transplant patients. Five cases and a review of the literature.| | PubMed
- Superior results of well matched cadaveric grafts as compared to parental grafts.| | PubMed
- Cryopreservation of vein grafts.| | PubMed